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Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions |
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| Authors: | Dr Svenja Morsbach Dr Grazia Gonella Prof?Dr Volker Mailänder Dr Seraphine Wegner Dr Si Wu Prof?Dr Tobias Weidner Dr Rüdiger Berger Dr Kaloian Koynov Prof?Dr Doris Vollmer Dr Noemí Encinas Dr Seah Ling Kuan Dr Tristan Bereau Prof Kurt Kremer Prof?Dr Tanja Weil Prof?Dr Mischa Bonn Prof?Dr Hans‐Jürgen Butt Prof?Dr Katharina Landfester |
| Affiliation: | 1. Max Planck Institute for Polymer Research, Mainz, Germany;2. Department of Dermatology, University Medical Center Johannes Gutenberg-University Mainz, Mainz, Germany;3. Department of Chemistry, Aarhus University, Aarhus C, Denmark |
| Abstract: | Once materials come into contact with a biological fluid containing proteins, proteins are generally—whether desired or not—attracted by the material's surface and adsorb onto it. The aim of this Review is to give an overview of the most commonly used characterization methods employed to gain a better understanding of the adsorption processes on either planar or curved surfaces. We continue to illustrate the benefit of combining different methods to different surface geometries of the material. The thus obtained insight ideally paves the way for engineering functional materials that interact with proteins in a predetermined manner. |
| Keywords: | characterization engineering interfaces nanomaterials protein adsorption |
