Sulfonated polyaniline‐graphene oxide hybrids: Synthesis and effect of monomer composition on the electrochemical signal for direct DNA detection |
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| Authors: | Le Meng Huaiyin Chen Tong Ge Tao Yang Kui Jiao |
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| Affiliation: | 1. Key Laboratory of Sensor Analysis of Tumor Marker of Education Ministry, Shandong Provincial Key Laboratory of Biochemical Analysis, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, China;2. Huangdao Entry‐Exit Inspection and Quarantine Bureau, Qingdao, People's Republic of China |
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| Abstract: | A variety of sulfonated polyaniline‐graphene oxide (SPAN‐GNO) nanocomposites based on GNO, aniline (ANI) and m‐aminobenzenesulfonic acid (ABSA) are prepared via changing the mole ratio of ANI to ABSA for the comparison of DNA sensing behavior. Self‐signals of SPAN‐GNO are employed for estimating the effect of preparation conditions component, monomer composition (mole ratio of ANI to ABSA), and reaction time] on DNA immobilization and hybridization detection. Then, we find herein that the mole ratio of ANI to ABSA plays a lead role over other factors on hybridization efficiency. Meanwhile, the parallel experiments using methylene blue as the classic indicator verifies this conclusion. The results show that, by comparison with other mole ratio SPAN‐GNO nanocomposites‐modified electrodes, the mole ratio (2:3) exhibits the widest dynamic detection range from 1.0 × 10?14 to 1.0 × 10?6 M, as well as the lowest detection limit (3.06 × 10?15 M). © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016 , 54, 1762–1773 |
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| Keywords: | composites conducting polymers nanocomposites |
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