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New Highly Oxidized Formamidobisabolene‐Derived Sesquiterpenes from a Hainan Sponge Axinyssa variabilis
Authors:Hai‐Li Liu  Duo‐Qing Xue  Si‐Han Chen  Xu‐Wen Li  Yue‐Wei Guo
Affiliation:1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, P. R. China;2. +86‐21‐50805813+86‐21‐50805813
Abstract:
Two new highly oxidized formamidobisabolene sesquiterpenes ( 1 and 2 ), together with seven known related analogues ( 3 – 9 ), were isolated from a Hainan sponge Axinyssa variabilis. Their structures were determined by extensive 1D‐ and 2D‐NMR and MS spectra analyses, and by comparison of their spectroscopic data with those of the related model compounds. The plausible biosynthetic relationship between compounds 1 – 9 has also been described.
Keywords:Bisabolene  Nitrogenous sesquiterpenes  Hainan sponge     Axinyssa variabilis     Biosynthetic pathway
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