Synthesis of New Triazole and Oxadiazole Derivatives of Quinazolin‐4(3H)‐one and Their Antimicrobial Activity |
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| Authors: | Kotla Veena Vani Garlapati Ramesh Chunduri Venkata Rao |
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| Affiliation: | Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh, India |
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| Abstract: | A series of new triazole derivatives of quinazolin‐4(3H)‐one and new oxadiazole derivatives of quinazolin‐4(3H)‐one were synthesized. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR and mass spectral data. All the newly synthesized compounds were screened for antibacterial activity against Staphylococcus aureus, Bacillus subtilis (gram‐positive bacteria), Escherichia coli, Pseudomonas aeruginosa (gram‐negative bacteria), and antifungal activity was carried out against Candida albicans and Aspergillus niger. |
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