Synthesis and Characterization of GaIII,YIII, and LuIII Complexes with Etifenin and Analogues |
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| Authors: | Michel Pfeifer‐Leeg Gergely Szabó Zsolt Baranyai Tobias Niksch Wolfgang Weigand Martin Freesmeyer |
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| Affiliation: | 1. Clinic of Nuclear Medicine, University Hospital Jena, Bachstra?e 18, 07743 Jena, Germany;2. Department of Inorganic and Analytical Chemistry, University of Debrecen, Egyetem tér 1, 4010, Debrecen, Hungary;3. Institute for Inorganic and Analytical Chemistry, Friedrich‐Schiller‐University Jena, Humboldtstra?e 8, 07743 Jena, Germany |
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| Abstract: | Complexes of etifenin ( 1a ), disofenin ( 1b ), and mebrofenin ( 1c ) with GaIII, YIII, and LuIII were synthesized and characterized by NMR spectroscopy and UV/Vis spectroscopy. Stability and protonation constants of the complexes of 1a were determined by potentiometry and distribution diagrams were calculated. It was shown that the YIII and LuIII species are most stable as bis chelates at higher pH, whereas the GaIII complex degrades at pH < 4.5. |
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| Keywords: | N O ligands Amides Gallium Yttrium Lutetium Potentiometry |
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