Bulk Modification of Carbon Paste Electrode with Bi2O3 Nanoparticles and Its Application as an Electrochemical Sensor for Selective Sensing of AntiHIV Drug Nevirapine |
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| Authors: | Nagappa L Teradal J Seetharamappa |
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| Affiliation: | Department of Chemistry, Karnatak University, Dharwad‐580?003, India |
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| Abstract: | Bi2O3 nanoparticles were synthesized by solution combustion method and utilized for fabrication of an electrochemical sensor carbon paste electrode modified with Bi2O3 (CPE‐Bi2O3)] for nevirapine (NVP). Electrode materials were characterized by XRD, FTIR, TG‐DTA, AFM and SEM‐EDS methods. CPE‐Bi2O3 was electroreduced (Er) in KOH in the potential range of ?1.3–0 V to obtain CPE‐ErBi2O3. CPE‐ErBi2O3 exhibited electrocatalytic activity towards the oxidation of NVP. Under optimized conditions, linearity between the peak current and NVP concentration was observed in the range of 0.05–50 µM. Further, the sensor was used for the assay of NVP in tablets and biological samples. |
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| Keywords: | CPE‐ErBi2O3 Nevirapine Electrocatalytic activity Analytical applications |
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