Voltammetric Behavior of Testosterone on Bismuth Film Electrode: Highly Sensitive Determination in Pharmaceuticals and Human Urine by Square‐Wave Adsorptive Stripping Voltammetry |
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| Authors: | Abdulkadir Levent Ahmet Altun Süleyman Taş Yavuz Yardım Zühre Şentürk |
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| Affiliation: | 1. Batman University, Health Services Vocational College, 72100 Batman, Turkey;2. Yüzüncü Y?l University, Faculty of Pharmacy, Department of Analytical Chemistry, 65080 Van, Turkey;3. Yüzüncü Y?l University, Faculty of Science, Department of Analytical Chemistry, 65080 Van, Turkey tel: 90?432?2251024;4. fax: 90?432?2251188 |
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| Abstract: | In this paper, an electrochemical application of bismuth‐film electrode (BiFE) fabricated via ex‐situ electrodeposition onto a glassy carbon electrode for testosterone determination was investigated in aqueous and aqueous/surfactant solutions. In cyclic voltammetry, the compound showed one irreversible and adsorption‐controlled reduction peak. The BiFE revealed good linear response in the examined concentration range of 1 to 45 nmol L?1 testosterone in Britton? Robinson buffer, pH 5.0 containing 3 mmol L?1 cetyltrimethylammonium bromide. The limit of detection was 0.3 nmol L?1 (0.09 ng mL?1). Finally, the BiFE was satisfactorily applied for quantitation of testosterone in both pharmaceutical (oil‐based ampoule) and biological (human urine) samples. |
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| Keywords: | Adsorptive stripping voltammetry Bismuth‐film electrode Cetyltrimethylammonium bromide Pharmaceutical and biological samples Testosterone |
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