Determination of Ethambutol in Aqueous Medium Using an Inexpensive Gold Microelectrode Array as Amperometric Sensor |
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Authors: | A E B Lima G E Luz Jr N C Batista E Longo L S Cavalcante R S Santos |
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Affiliation: | 1. PPGQ‐GERATEC‐DQ‐Universidade Estadual do Piauí, Rua: Jo?o Cabral, N. 2231, P.O. Box 381, 64002‐150, Teresina, PI, Brazil, Tel: +55?86?3213‐2547, Mob: +55?86?99940?9556;2. CDMF‐Universidade Estadual Paulista, P.O. Box 355, 14801‐907, Araraquara‐SP, BrazilSupporting information for this article is available on the WWW underhttp://dx.doi.org/10.1002/elan.201500600. |
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Abstract: | In this paper, gold microelectrode array (Au‐MEA) were employed to determination of ethambutol in aqueous medium. Au‐MEA was constructed with an electronic microchip integrated circuit. The standard curve (analytical curve) was constructed for a single microelectrode (ME) in a concentration range of 5.0×10?5 to 2.0×10?3 mol L?1, allowing estimation of both the limit of detection (LOD) (4.73×10?5 mol L?1) and the limit of quantification (LOQ) (1.57×10?4 mol L?1) for ethambutol. When the MEA was utilized, the LOD and LOQ were 1.55×10?7 and 5.18×10?7 mol L?1, respectively. Our results indicated that Au‐MEA can be utilized as amperometric sensors for ethambutol determination in aqueous media. |
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Keywords: | Amperometric Sensor Gold microelectrode array Ethambutol |
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