Two New Alkaloids from the Roots of Aconitum sinomontanum Nakai |
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| Authors: | Bin Xu Jiehua Xue Junjie Tan Shanhao Jiang Fujiang Guo Yiming Li |
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| Affiliation: | 1. School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.?R. China (phone: +86‐21‐51322191;2. fax: +86‐21‐51322193);3. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China |
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| Abstract: | Two new alkaloids, ranaconidine (=20‐ethyl‐1α,14α,16β‐trimethoxyaconitane‐4,7,8,10‐tetrol; 1 ) and N‐(chloromethyl)taspine (=1‐[2‐(N‐(chloromethyl)‐N,N‐dimethylaminium)ethyl]‐3,8‐dimethoxybenzopyrano[5,4,3‐cde]benzopyran‐5,10‐dione; 2 ), together with two known compounds, i.e., benzethonium chloride ( 3 ) and ranaconine ( 4 ) were isolated from the roots of Aconitum sinomontanum Nakai . The structures of the compounds were elucidated on the basis of spectral evidences and in the comparison with previously published data. |
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| Keywords: | Aconitum sinomontanum Norditerpenoids Alkaloids Ranaconidine Taspine, N‐(chloromethyl)‐ |
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