CuFeO2/tetrabutylammonium bromide catalyzes selective synthesis of 1,4‐disubstituted 1,2,3‐triazoles in neat water at room temperature |
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| Authors: | Abdol R Hajipour Morteza Karimzadeh Farzaneh Fakhari Hirbod Karimi |
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| Affiliation: | 1. Pharmaceutical Research Laboratory, Department of Chemistry, Isfahan University of Technology, Isfahan, Islamic Republic of Iran;2. Department of Neuroscience, University of Wisconsin, Medical School, Madison, WI, USA |
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| Abstract: | A completely green medium including water as a solvent and antiviral CuFeO2 as a catalyst is described for the synthesis of 1,4‐disubstituted 1,2,3‐triazoles. Excellent yields of products are obtained at room temperature. Cost effectiveness, high stability and high recyclability of CuFeO2 along with antiviral properties of the catalyst make it a unique catalyst for cycloadditions of phenylacetylene with a wide variety of aryl halides. Copyright © 2016 John Wiley & Sons, Ltd. |
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| Keywords: | 1 2 3‐triazoles azide cycloaddition delafossite ligand‐free phenylacetylene |
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