Paradigm Shift from Alkaline (Earth) Metals to Early Transition Metals in Fluoroorganometal Chemistry: Perfluoroalkyl Titanocene(III) Reagents Prepared via Not Titanocene(II) but Titanocene(III) Species |
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| Authors: | Motohiro Fujiu Ryota Hashimoto Yuzo Nakamura Prof. Dr. Kohsuke Aikawa Prof. Dr. Shigekazu Ito Prof. Dr. Koichi Mikami |
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| Affiliation: | Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo 152‐8552 (Japan), Fax: (+81)?3‐5734‐2776 |
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| Abstract: | Perfluoroalkyl (RF) titanocene reagents [Cp2TiIIIRF] synthesized via [Cp2TiIIICl] rather than [Cp2TiII] show new types of perfluoroalkylation reactions. The [Cp2TiIIIRF] reagents exhibit a wide variety of reactivity with carbonyl compounds including esters and nitriles, and selectivities far higher than those reported for conventional RFLi and RFMgX reagents. |
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| Keywords: | alkylation fluorine metallocenes synthetic methods titanium |
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