Ruthenium‐Catalyzed Oxidant‐Free Allylation of Aromatic Ketoximes with Allylic Acetates at Room Temperature |
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| Authors: | Rajendran Manikandan Padmaja Madasamy Dr Masilamani Jeganmohan |
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| Affiliation: | Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021 (India) |
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| Abstract: | Substituted aromatic ketoximes reacted efficiently with allylic acetates in the presence of {RuCl2(p‐cymene)]2} and AgSbF6 in 1,2‐dichloroethane at ambient temperature, providing ortho‐allyl aromatic ketoximes in a highly regioselective manner without an oxidant. In the reaction, the acetate group of allyl acetate acts as a base to activate the C?H bond of aromatics. Later, ortho‐allyl aromatic ketoximes were converted into ortho‐allyl aromatic ketones in the presence of HCl. |
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| Keywords: | allylation allylic compounds C H activation ketoximes ruthenium |
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