Oxidative Cross‐Coupling of Allenyl Ketones and Organoboronic Acids: Expeditious Synthesis of Highly Substituted Furans |
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| Authors: | Ying Xia Dr Yamu Xia Rui Ge Zhen Liu Dr Qing Xiao Dr Yan Zhang Prof?Dr Jianbo Wang |
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| Affiliation: | 1. Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871 (China);2. College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042 (China) |
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| Abstract: | Allenyl ketones are employed as coupling partners in palladium‐catalyzed oxidative cross‐coupling reactions with organoboronic acids. This reaction constitutes an efficient methodology for the synthesis of highly substituted furan derivatives. Palladium‐carbene migratory insertion is proposed as the key step in this transformation. |
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| Keywords: | allenes carbenes cross‐coupling furans palladium |
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