天然C19-二萜生物碱的研究进展及其核磁共振波谱特征

doi:10.11938/cjmr20182655

摘要/Abstract

摘要： C₁₉-二萜生物碱是二萜生物碱中数量最多的一类，主要分布于毛茛科的乌头属、翠雀属和飞燕草属植物中．C₁₉-二萜生物碱结构复杂、生理活性显著，一直吸引着科研工作者的广泛关注．本文主要对2010~2018年报道的天然来源C₁₉-二萜生物碱的研究进行总结，并归纳了C₁₉-二萜生物碱各子类型的核磁共振（NMR）结构特征和解析方式，以期为C₁₉-二萜生物碱的深入研究及开发提供参考依据．

关键词: C₁₉-二萜生物碱, 核磁共振(NMR)波谱, 结构解析, 乌头属, 翠雀属

Abstract: Majority of diterpenoid alkaloids are C₁₉-diterpenoid alkaloids found in the plants from the genera Aconitum, Delphinium and Consolida (Ranunculaceae). C₁₉-diterpenoid alkaloids have attached lots of research interests due to their complex structures and remarkable pharmacological activities. This paper reviewed the structural features of natural C₁₉-diterpenoid alkaloids reported in literature from 2010 to 2018, focusing on the NMR spectral characteristics of different subtypes of C₁₉-diterpenoid alkaloids and how their structures could be elucidated from the NMR data. The work may provide a reference for the further research and development of C₁₉-diterpenoid alkaloids.

Key words: C₁₉-diterpenoid alkaloids, nuclear magnetic resonance (NMR)spectroscopy, structural elucidation, Aconitum, Delphinium

中图分类号:

O482.53

尹田鹏, 罗智慧, 蔡乐, 丁中涛. 天然C₁₉-二萜生物碱的研究进展及其核磁共振波谱特征[J]. 波谱学杂志, 2019, 36(1): 113-126.

YIN Tian-peng, LUO Zhi-hui, CAI Le, DING Zhong-tao. Research Progress and NMR Spectral Features of Natural C₁₉-Diterpenoid Alkaloids[J]. Chinese Journal of Magnetic Resonance, 2019, 36(1): 113-126.

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天然C₁₉-二萜生物碱的研究进展及其核磁共振波谱特征

Research Progress and NMR Spectral Features of Natural C₁₉-Diterpenoid Alkaloids

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